With COVID-19 Expected to Climb This Winter, Could a Resurgence in MIS-C Be Far Behind?

With COVID-19 Expected to Climb This Winter, Could a Resurgence in MIS-C Be Far Behind? As JUCM News has reported, cases of COVID-19 are expected to climb as we move into the winter months. While some signs point to a “season” that will be less severe than the past couple of years, others paint a less optimistic picture. Either way, it is essential to keep in mind that while otherwise healthy children have been less likely than other patient types to suffer severe consequences from SARS-CoV-2 infection, the threat of multisystem inflammatory syndrome in children (MIS-C) must be recognized. As reported by Medpage Today, a new diagnostic model may be very helpful in that regard. Clinicians from Vanderbilt University Medical Center in Nashville, TN found that a constellation of signs—hypotension and/or fluid resuscitation, new rash, abdominal pain, and serum sodium concentration—showed a concordance index of 0.91 compared with clinical diagnoses in retrospective analysis of 127 children suspected of having MIS-C. Given the small sample size, further study is needed to confirm or repudiate the model. For more details on MIS-C itself from an urgent care perspective, read Multisystem Inflammatory Syndrome in Children (MIS-C): Who Should Not Be Misc’ed?here.