New CKM Syndrome Combines Multiple Chronic Conditions

New CKM Syndrome Combines Multiple Chronic Conditions

The American Heart Association introduced the concept of a new medical condition called cardiovascular-kidney-metabolic syndrome (CKM) in a recent article in Circulation. The rising incidence of multiple chronic health issues in younger Americans, particularly obesity, diabetes, and heart and kidney disease, calls for earlier diagnosis and risk assessment, the association says. The synergy between metabolic risk factors, such as abdominal fat, high blood pressure, high cholesterol, and elevated blood sugar, has long-term effects on health …

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Gestational Diabetes and Long-Term Health

Gestational Diabetes and Long-Term Health

A recent study published in JAMA Internal Medicine involving more than 91,000 female participants 25 to 42 years old reveals that moms with a history of gestational diabetes face a slightly increased risk of mortality over a 30-year period compared to those without a history of the condition. The researchers found that women reporting a gestational diabetes diagnosis were 1.28 times more likely to experience mortality—a rate of 1.74 per 1,000 person-years compared to 1.49 …

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Delicious Relief from Functional Dyspepsia

Delicious Relief from Functional Dyspepsia

A Thai study published in BMJ Evidence-Based Medicine concluded that curcumin, a natural compound derived from turmeric, had comparable efficacy to omeprazole in treating functional dyspepsia. Baseline dyspepsia scores were comparable between the groups participating in this randomized, double-blind, controlled trial of 151 patients. They were divided into those receiving curcumin alone, those receiving  omeprazole alone, and those receiving curcumin plus omeprazole. Participants in the combination group took two 250 mg curcumin capsules, four times a …

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Researchers Develop Mpox Point of Care Test

Researchers Develop Mpox Point of Care Test

Last spring, a global outbreak of mpox (formerly known as “monkey pox”) spread to 110 countries. Cases in the United States as of last month have reached a total of 30,767, according to the Centers for Disease Control and Prevention. Meanwhile, researchers have found that a newly developed point-of-care assay for the rapid detection of the mpox virus has the potential for use in “low-resource and remote settings,” allowing for rapid point-of-care diagnosis. The results …

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Parents Accidentally Double Dose Kids’ ADHD Meds

Parents Accidentally Double Dose Kids’ ADHD Meds

Researchers at Nationwide Children’s Hospital in Ohio found a disturbing number of preventable mistakes made by parents and caregivers involving medications given to children for attention deficit/hyperactivity disorder (ADHD). The most common error (54%) was accidental double dosing. What’s more concerning is that the rate of errors in giving kids ADHD medications has risen significantly over the past two decades. From 2000 through 2021, errors increased by almost 300%. Kids between the ages 6 and …

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Loss of Taste or Smell a Less Likely COVID-19 Symptom

Loss of Taste or Smell a Less Likely COVID-19 Symptom

Clinical teams are facing some difficulty in distinguishing between COVID-19, allergies, and the common cold this season because some traditional COVID-19 symptoms—such as dry cough and loss of taste or smell—have now become less common. The Zoe COVID Symptom Study in the UK supports this trend, with physicians observing milder disease, mostly concentrated in the upper respiratory tract. Sore throat was often identified as the first noticeable symptom, as reported in an NBC News article. …

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COVID Cases Are Up, but New Data Offer Evidence on How to Keep Patients Out of the Hospital

COVID Cases Are Up, but New Data Offer Evidence on How to Keep Patients Out of the Hospital

As with all things related to COVID-19, early efforts to treat patients sufficiently to avoid hospitalization had the appearance of throwing the proverbial spaghetti at the wall to see what stuck. Over time, data started to illuminate which approaches offered the most promise. Now, with multiple states tracking a gradual uptick in both positive cases and hospitalizations as fall approaches, new research published in Reviews in Medical Virology supplements existing data showing that nirmatrelvir-ritonavir (Paxlovid) …

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Years After Infection, Patients Are Grappling with New COVID-Related Disability. Be Vigilant

Years After Infection, Patients Are Grappling with New COVID-Related Disability. Be Vigilant

As long as 2 years after recovering from COVID-19, some patients who were healthy before becoming infected now experience blood clots, diabetes, neurological complications, fatigue, and mental health issues thought to be related to the virus. The authors of research published in the journal Nature measured disability adjusted life years (DALY) in patients who had recovered from COVID-19 or developed long COVID, with each DALY unit reflecting 1 year of healthy life lost due to …

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New Regimens, Similar Conclusions for PrEP. Do They Change Anything for Urgent Care?

New Regimens, Similar Conclusions for PrEP. Do They Change Anything for Urgent Care?

The U.S. Preventive Services Task Force reported 4 years ago that oral preexposure prophylaxis (PrEP) reduced the likelihood of HIV infection in adults at increased risk for infection. At the time, offering PrEP in urgent care was a controversial prospect; while there was little debate as to the public health benefits, some UC operators found the complex side-effects profile daunting for a setting largely dedicated to episodic care. Now a meta-analysis of newer PrEP regimens …

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Don’t Jump to Conclusions If That BP Reading Seems Off; You Might Want to Check the Equipment

Don’t Jump to Conclusions If That BP Reading Seems Off; You Might Want to Check the Equipment

It’s not unusual for patients presenting to urgent care to have elevated blood pressure that doesn’t necessarily indicate that they have hypertension. Even extreme blood pressure may not mean the patient needs to be dispatched to the emergency room. There are any number of possible explanations for high BP reading besides “hypertension” in urgent care patients—pain, anxiety, and stimulant use being just a few. An article just published in JAMA Internal Medicine highlights another possible …

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