Journal of Urgent Care Medicine

Popular Osteoporosis Drug Increases Risk of Hypocalcemia

The Food and Drug Administration (FDA) recently added a boxed warning to the osteoporosis drug denosumab (Prolia) due to the heightened risk of severe hypocalcemia in patients with advanced chronic kidney disease (CKD). The agency’s decision, based on new evidence and a JAMA review, notes that denosumab increases the risk of severe hypocalcemia compared to bisphosphonates, particularly in CKD patients on dialysis. Severe hypocalcemia can manifest with symptoms like confusion, seizures, irregular heart rhythm, fainting, …

JN.1 Notorious For High Infection Rates But Less Illness Severity

The JN.1 variant of the SARS-CoV-2 virus appears to be more contagious than other members of the Omicron family, driving indicators of infection levels and COVID-19 illness. Even so, this currently circulating variant seems to produce a more mild illness with less need for medical attention. Data from the Centers for Disease Control and Prevention as reported in JAMA Network shows emergency department visits for COVID-19 are down 21% this year, and the percentage of …

Leg Strength May Be A Clue For Heart Failure After ACS

The European Journal of Preventive Cardiology recently published research demonstrating that a higher level of quadriceps isometric strength (QIS) was strongly associated with a lower risk of developing heart failure (HF) after acute coronary syndrome (ACS). Researchers studied the relationship between QIS and the risk of developing HF in patients with ACS using HF admissions as the endpoint. QIS is a skeletal muscle strength indicator, and study authors classified 1,053 patients with ACS without prior …

Linaclotide Relieves Constipation in Kids

The guanylate cyclase C agonist, linaclotide (Linzess), doubled weekly bowel movements among children age 6 and younger, helping to treat pediatric patients with functional constipation, according to a study published in Lancet Gastroenterology & Hepatology. As a recently approved treatment option, linaclotide demonstrated improvement in frequency over placebo with 57% of patients in the treatment group experiencing a spontaneous bowel movement within the first 48 hours of receiving the drug. Authors also observed improvement in …

ACE Inhibitors Show Less Protection Against Stroke Mortality

In a study presented in JAMA Network Open, researchers sought to determine the difference in the long-term risk of mortality and morbidity outcomes for adults with hypertension taking a thiazide-type diuretic, calcium channel blocker (CCB), or angiotensin-converting enzyme (ACE) inhibitor. Their secondary analysis found that mortality due to cardiovascular disease was similar among patients, regardless of which treatment was used. However, compared with the diuretic group, the ACE inhibitor group had a 19% increased risk …

Regulators Consider Standard Licensing for UC Centers

Massachusetts regulators are considering new measures to create a standard licensure for urgent care (UC) centers in the state in an effort to “apply care standards and improve quality of care,” according to the Worcester Business Journal. Officials also want the ability to collect uniform quality-of-care data from all UC operators, noting that last year, only about one-fourth of the centers in the state reported their data to the US Centers for Disease Control and …

More Providers Billing For Patient Text Messages

According to a JAMA study, providers are increasingly billing patient-initiated text messages as “telemedicine.” Not to be confused with synchronous video visits, more than 100,000 such text-message charges were billed per month in 2022, and monthly volume increased 40% from Q4 of 2021 to Q4 of 2022. That’s the same comparison period in which urgent care visits were down significantly as the SARS-CoV-2 Omicron variant emerged. Top UC diagnoses: “What really stands out are the top …

Drug Company Launches DTC Model for Weight Loss Prescriptions

Pharmaceutical company Eli Lilly just launched its own telehealth website where patients can access physician appointments and the prescription drug tirzepatide (Mounjaro and Zepbound) for weight loss. The new LillyDirect platform also offers free home-delivery service, but it will not provide discounts on tirzepatide. As described in a news story in People, Mounjaro is approved to treat type 2 diabetes, and Zepbound is approved to treat obesity, each with a list price of more than $1,000 for a …

GoHealth Adds New Leaders, Announces Expansion Plans

GoHealth Urgent Care recently announced plans to craft new health system partnerships and to open its 300th center location by the end of the year, according to a company press release. GoHealth currently operates about 270 centers in several states. At the same time, the company also announced leadership expansions to complement its growth strategy. Todd Latz, GoHealth’s Chief Executive Officer, noted two newly created roles on the executive team: Tom Oram will become the Chief …

Studies Find No Increased Risk of Suicide With Semaglutide

The glucagon-like peptide 1 (GLP-1) receptor agonist semaglutide (Wegovy, Ozempic) was found to demonstrate no increased risk of suicidal ideation in patients with obesity or type 2 diabetes, according to retrospective analyses of electronic health records examining these patient populations, published in Nature Medicine. Researchers’ analysis of 240,618 patients who were overweight/obese showed that those taking semaglutide had a significantly lower risk (0.11%) of suicidal ideation compared with those using non-GLP-1 anti-obesity medications (0.43%). In …