Head-to-Head Study Compares GLP-1 Weight Loss

Head-to-Head Study Compares GLP-1 Weight Loss

In a pharmaceutical head-to-head, tirzepatide was found to provide 47% greater relative weight loss compared to semaglutide. On average, patients using tirzepatide lost 50.3 lbs (22.8 kg), and those using semaglutide lost 33.1 lbs (15.0 kg) after 72 weeks. In addition, for the study’s secondary endpoint, 31.6% of people taking tirzepatide achieved at least 25% body weight loss compared to 16.1% of those taking semaglutide. The randomized, open-label trial included 751 participants across the United …

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UnitedHealth Group CEO Killed Near NY Investor Day Event

UnitedHealth Group CEO Killed Near NY Investor Day Event

Brian Thompson, CEO of UnitedHealthcare’s insurance division, was shot and killed outside of a hotel in New York City on December 4, according to news reports. The 50-year-old Thompson has worked for the company for 20 years and was promoted to the chief executive position in 2021. UnitedHealth Group leadership canceled the day’s scheduled investor event immediately after the incident. He was described as an “extraordinary person” in a video sent to employees. Thompson was …

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Which Children Receive First-Line Antibiotics in Urgent Care Most Often? 

Which Children Receive First-Line Antibiotics in Urgent Care Most Often? 

In a new study of children 6 to 18 months of age, researchers found the odds of receiving first-line antibiotic therapy in pediatric urgent care centers (PUCs) were lower among White children and those with commercial insurance than in other groups. Authors of the study presented in Infection Control & Hospital Epidemiology looked at guideline-recommended first-line antibiotics for acute respiratory infections (ARIs) for 396,340 encounters at 28 PUCs in the United States over 1 year. …

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UK Begins To Stockpile H5N1 Vaccines

UK Begins To Stockpile H5N1 Vaccines

The United Kingdom’s Health Security Agency has now contracted with a supplier to purchase more than 5 million doses of human H5N1 avian flu vaccine to prepare the country should an avian flu pandemic occur. The virus has been causing a prolonged global outbreak with new cases emerging in humans recently—although the risk still remains quite low. Poultry and dairy cattle are the most likely animals to experience outbreaks of the virus, and thousands of …

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New FBI Advisory Warns of Hackers Targeting Healthcare

New FBI Advisory Warns of Hackers Targeting Healthcare

The Federal Bureau of Investigation and a number of its partners issued a joint advisory last week, highlighting cybercriminal activities by a ransomware group known as BianLian. With a history of attacking the healthcare sector, BianLian has targeted various other industries as well. The group gains system access using legitimate remote desktop protocol credentials then steals system-user credentials. The hackers then extort the target organizations by threatening to publicly release the stolen data. By using …

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Marketplaces Signing Up New Members During Open Enrollment 

Marketplaces Signing Up New Members During Open Enrollment 

Almost half a million Americans who currently do not have health insurance have signed up for a new 2025 health plan through the federal Health Insurance Marketplace so far, the Centers for Medicare & Medicaid Services reports. To put the numbers in context, about 8.2% of Americans (27 million people) were uninsured this year, compared to 16% in 2010, according to federal data. And there are still a few weeks left in open enrollment. The …

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FDA Keeping Tabs on Montelukast Suicide Risk

FDA Keeping Tabs on Montelukast Suicide Risk

The Food and Drug Administration (FDA) presented the preliminary results of new research on montelukast at the American College of Toxicology meeting recently, describing potential side-effect risks for the oral asthma drug. Montelukast may be leading to mental health conditions and suicide by attaching to multiple brain receptors that are involved in psychiatric functioning, researchers say. According to Reuters, thousands of patients have reported neuropsychiatric episodes, prompting the FDA to launch a comprehensive investigation and …

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VillageMD Top Exec Resigns Amid Financial Backslide 

VillageMD Top Exec Resigns Amid Financial Backslide 

CEO Tim Barry, the founder and top executive of VillageMD, is stepping down from his role as the company faces significant financial difficulties. Majority owner Walgreens Boots Alliance has reported substantial losses amounting to billions of dollars, according to Forbes. VillageMD has struggled for more than a decade to attract patients to its clinics located within Walgreens retail stores. This has led to a sharp reduction in its intended expansion plans to stand up clinics …

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UC Medical Director Nesheiwat Tapped for Surgeon General

UC Medical Director Nesheiwat Tapped for Surgeon General

President-elect Trump has announced his intended appointment of Janette Nesheiwat, MD, to be the next surgeon general, according to NPR. She is currently a medical director for CityMD and has contributed to Fox News. With a specialization in emergency and family medicine, she is known for supporting vaccine efforts with an emphasis on the balance of risk and benefit. CityMD merged with Summit Health and was ultimately acquired by VillageMD in early 2023 for $8.9 …

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AAP Offers Guidelines for Pediatric Opioid Prescribing

AAP Offers Guidelines for Pediatric Opioid Prescribing

The American Academy of Pediatrics (AAP) has issued its first clinical practice guideline on prescribing opioids for outpatient acute pain management in children, published in Pediatrics. The guideline recommends using immediate-release opioids at the lowest dose for age- and weight-appropriateness, with an initial supply of no more than 5 days unless the pain is due to trauma or surgery requiring longer treatment. Codeine and tramadol should not be prescribed to children under 12, adolescents with …

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