Comparing Outcomes for Outpatients Treated With Cephalexin for Uncomplicated Cystitis: Is QID Dosing Necessary?

Comparing Outcomes for Outpatients Treated With Cephalexin for Uncomplicated Cystitis: Is QID Dosing Necessary?

Urgent Message: Patients commonly seek unscheduled care for urinary tract infections (UTIs). Cephalexin is among the most frequently prescribed antibiotics for acute UTI treatment, however, dosing regimens lack standardization. In this small observational study, similar rates of clinical cure and adherence were observed with cephalexin 500 mg dosed every 12 hours vs every 6 hours in patients with cystitis, calling into question whether QID (4 times per day) dosing is necessary. Cassandra Lopane, PharmD; Erica …

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