The guanylate cyclase C agonist, linaclotide (Linzess), doubled weekly bowel movements among children age 6 and younger, helping to treat pediatric patients with functional constipation, according to a study published in Lancet Gastroenterology & Hepatology. As a recently approved treatment option, linaclotide demonstrated improvement in frequency over placebo with 57% of patients in the treatment group experiencing a spontaneous bowel movement within the first 48 hours of receiving the drug. Authors also observed improvement in …
Read More![Linaclotide Relieves Constipation in Kids Linaclotide Relieves Constipation in Kids](https://www.jucm.com/wp-content/uploads/2024/01/Constipation-kids-Pediatric-Stomach-Ache-Young-White-Female-Child-Holding-Upset-Tummy-with-Sister-or-Mother-Comforting-Her-380x253-1.jpg)