Preventing recurrent urinary tract infection (RUTI) in children usually involves antibiotic prophylaxis. A new meta-analysis in Pediatrics of 23 randomized controlled trials found that for children with a history of RUTI, the antibiotic nitrofurantoin and cranberry products— both cranberry juice and tablets as supplementation—appeared to decrease the incidence of symptomatic episodes. Nitrofurantoin significantly lowering odds of symptomatic UTI episodes during prophylaxis, whether compared with controls (odds ratio [OR] 0.21, 95% confidence interval [CI] 0.07-0.65, P=0.007) …
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