SEAN M. McNEELEY, MD Longer-Term Antibiotic Treatment and Persistent Lyme Disease Symptoms Key point: Longer therapy for Lyme disease is not helpful. Citation: Berende A, ter Hofstede HJ, Vos FJ, et al. Randomized trial of longer-term therapy for symptoms attributed to Lyme disease. N Engl J Med. 2016;374:1209–1220. Lyme disease continues to be in the news because persistent symptoms after infection are of great concern. In a double- blind, placebo-controlled study, researchers gave antibiotics for …
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