San Francisco Syncope Rule

San Francisco Syncope Rule: Less Sensitive Than Previously Reported Key point: An independent validation study demonstrated a sensitivity of only 74% for predicting serious outcomes. Citation: Birnbaum A, Esses D, Bijur P, et al. Failure to validate the San Francisco Syncope Rule in an independent emergency department population. Ann Emerg Med. 2008;52(2):151-159. Most patients who present with syncope have benign etiologies, but, for some, syncope is caused by a potentially life-threaten- ing condition. Differentiating between …

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