High Dose Stimulants Present Elevated Risk for Mania

High Dose Stimulants Present Elevated Risk for Mania

A recent study of adult emergency department (ED) admissions published in Psychiatry Online found that patients taking high doses of prescription amphetamine drugs such as Adderall (>30 mg dextroamphetamine equivalents) have a 5.28-fold increased risk for developing psychosis or mania. Researchers compared 1,374 cases of individuals presenting with first-episode psychosis or mania to 2,748 control patients with a psychiatric hospitalization for other conditions. Data analysis suggests that 81% of cases of psychosis or mania potentially …

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