Vasopressin Not Helpful for Out-of-Hospital Cardiac Arrest Key point: For now, epinephrine remains the only evidence- based drug option in CPR. Citation: Gueugniaud P-Y, David J-S, Chanzy E, et al. Vasopressin and epinephrine vs. epinephrine alone in cardiopulmonary re- suscitation. N Engl J Med. 2008;359:21-30. The ideal drug regimen for use in CPR is a subject of controversy. Epinephrine is the recommended vasopressor agent, but results of some studies suggest that combining epinephrine with vasopressin …
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