Liraglutide May Help Kids Under 12 Lose Weight

Liraglutide May Help Kids Under 12 Lose Weight

Liraglutide, the long-acting glucagon-like peptide-1 (GLP-1) drug, was approved for weight loss in among pediatric patients aged 12 and older who are obese. Recently, manufacturer Novo Nordisk found in a sponsored study that children between the ages of 6 and 12—a younger population—were able to reduce their body mass index by 7.4% in a 56-week trial using daily liraglutide injections, as published in the New England Journal of Medicine. The trial of 92 children met …

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GLP-1 Drugs Increasingly Used For Weight, Not Diabetes

GLP-1 Drugs Increasingly Used For Weight, Not Diabetes

A nationwide population-based study on prescribing trends published in the Annals of Internal Medicine found a significant increase in new users of GLP-1 receptor agonists who don’t have a diagnosis of type 2 diabetes. The proportion of new GLP-1 users with type 2 diabetes decreased from nearly 90% to about 70% from 2019 to 2023, according to a separate analysis of the findings in MedPage Today. Meanwhile, new users tend to be those prescribed the …

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Substantial Number of GLP-1 Drugs in the Pipeline Hint at Lower Future Costs

Substantial Number of GLP-1 Drugs in the Pipeline Hint at Lower Future Costs

Drugmakers are developing new iterations of GLP-1 weight loss drugs that could result in fewer side effects. According to a news item in Becker’s Hospital Review, 27 GLP-1 drugs are in development, but the majority of the data is based on animal studies or early-stage human trials. In one example, researchers are optimistic about the experimental drug petrelinitide, which was shown to reduce body weight by an average of nearly 9% at 16 weeks. It …

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Side Effects of New Weight Loss Medications

Side Effects of New Weight Loss Medications

Urgent message: With the epidemic of obesity and recent FDA-approval of weight loss drugs, urgent care providers should be on alert for patient presentations related to side effects of these agents. Introduction An estimated 154.7 million Americans over the age of 20 are currently overweight or obese. These Americans are at increased risk of disease, including diabetes mellitus, cardiovascular disease, end-stage renal disease and cancer. If current trends remain unchanged, an estimated $861 to $957 …

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