Ultimately, the patient was diagnosed with herpes zoster (shingles) with superficial cellulitis.
The treating physicians prescribed gabapentin & topical capsaicin for treatment of the resultant pain, and cephalexin for treatment of the superficial cellulitis.
It is notable that acyclovir was not prescribed.
While oral acyclovir 800 mg/day has been shown to decrease incidence of post-herpetic neuralgia at six months by almost 50 percent, its use is clinically most beneficial 48 to 72 hours after onset*—far earlier than our patient presented.
*Source: The effect of treating herpes zoster with oral acyclovir in preventing postherpetic neuralgia. A meta-analysis. Jackson JL, Gibbons R, Meyer G, et al. Arch Intern Med. 1997;157(8):909-912.
Case presented by John Phillip Sherrod, MD, David Boyd, MD, and Ronald Billips, MD, St. Francis Family Medicine, Midlothian, VA.
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